nlmixr2: Nonlinear Mixed Effects Models in Population PK/PD

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Version:	3.0.1
Depends:	nlmixr2data
Imports:	nlmixr2est (≥ 2.2.2), nlmixr2extra (≥ 2.0.10), rxode2 (≥ 2.1.3), lotri (≥ 0.4.3), nlmixr2plot (≥ 2.0.8), magrittr, crayon, cli
Suggests:	rmarkdown, knitr, devtools, ggplot2, testthat, n1qn1, withr
Published:	2024-10-28
DOI:	10.32614/CRAN.package.nlmixr2
Author:	Matthew Fidler [aut, cre], Yuan Xiong [ctb], Rik Schoemaker [ctb], Justin Wilkins [ctb], Wenping Wang [ctb], Mirjam Trame [ctb], Huijuan Xu [ctb], John Harrold [ctb], Bill Denney [ctb], Theodoros Papathanasiou [ctb], Teun Post [ctb], Richard Hooijmaijers [ctb]
Maintainer:	Matthew Fidler <matthew.fidler at gmail.com>
BugReports:	https://github.com/nlmixr2/nlmixr2/issues/
License:	GPL (≥ 3)
URL:	https://nlmixr2.org/, https://github.com/nlmixr2/nlmixr2/
NeedsCompilation:	no
Citation:	nlmixr2 citation info
Materials:	README NEWS
In views:	DifferentialEquations, HighPerformanceComputing, MixedModels, Pharmacokinetics
CRAN checks:	nlmixr2 results

Documentation:

Reference manual:

nlmixr2.pdf

Downloads:

Package source:	nlmixr2_3.0.1.tar.gz
Windows binaries:	r-devel: nlmixr2_3.0.1.zip, r-release: nlmixr2_3.0.1.zip, r-oldrel: nlmixr2_3.0.1.zip
macOS binaries:	r-release (arm64): nlmixr2_3.0.1.tgz, r-oldrel (arm64): nlmixr2_3.0.1.tgz, r-release (x86_64): nlmixr2_3.0.1.tgz, r-oldrel (x86_64): nlmixr2_3.0.1.tgz
Old sources:	nlmixr2 archive

Reverse dependencies:

Reverse depends:	babelmixr2
Reverse imports:	nlmixr2rpt, shinyMixR
Reverse suggests:	ggPMX, tidyvpc, xpose.nlmixr2

Linking:

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