Changes in version 0.99.6 - Real data example added. - Unit test modified. Changes in version 0.99.4 - Unit test added. - Coding modified in compliance with BioC requirement. Changes in version 0.99.3 - Slope test implemented. - Added a news file to track changes to the package. Changes in version 0.99.2 - Slope test implemented. - Added a news file to track changes to the package.