\usepackage {colortbl}
\definecolor{Bluec}{cmyk}{.60,0,0,0}
\begin{tabular}{l>{\columncolor{Bluec}}rr}
\large\textbf{Table title}\\[2mm]
\textbf{Description} & \textbf{Column 1}
             & \textbf{Column 2} \\[1mm]
Row one  & mmmmm & mmmm \\
Row two  &  mmmm &  mmm \\
Row three& mmmmm & mmmmm \\
Row four & mmmmm & mmmm \\
Totals   & mmmmm & mmmmm
\end{tabular}