TrialEmulation: Causal Analysis of Observational Time-to-Event Data

Implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>.

Version:	0.0.4.0
Depends:	R (≥ 4.0.0)
Imports:	broom (≥ 0.7.10), checkmate, data.table (≥ 1.9.8), DBI, duckdb, formula.tools, lifecycle, lmtest, methods, mvtnorm, parglm, Rcpp, sandwich
LinkingTo:	Rcpp
Suggests:	knitr, parsnip, rmarkdown, rpart, testthat (≥ 3.0.0), withr
Published:	2024-11-29
DOI:	10.32614/CRAN.package.TrialEmulation
Author:	Isaac Gravestock [aut, cre], Li Su [aut], Roonak Rezvani [aut] (Original package author), Julia Moesch [aut], Medical Research Council (MRC) [fnd], F. Hoffmann-La Roche AG [cph, fnd]
Maintainer:	Isaac Gravestock <isaac.gravestock at roche.com>
BugReports:	https://github.com/Causal-LDA/TrialEmulation/issues
License:	Apache License (≥ 2)
URL:	https://causal-lda.github.io/TrialEmulation/, https://github.com/Causal-LDA/TrialEmulation
NeedsCompilation:	yes
Language:	en-GB
Materials:	README NEWS
CRAN checks:	TrialEmulation results

Documentation:

Reference manual:	TrialEmulation.pdf
Vignettes:	Extending-TrialEmulation (source, R code) Getting-Started (source, R code) New Interface (source, R code)

Downloads:

Package source:	TrialEmulation_0.0.4.0.tar.gz
Windows binaries:	r-devel: TrialEmulation_0.0.4.0.zip, r-release: TrialEmulation_0.0.4.0.zip, r-oldrel: TrialEmulation_0.0.4.0.zip
macOS binaries:	r-release (arm64): TrialEmulation_0.0.4.0.tgz, r-oldrel (arm64): TrialEmulation_0.0.4.0.tgz, r-release (x86_64): TrialEmulation_0.0.4.0.tgz, r-oldrel (x86_64): TrialEmulation_0.0.4.0.tgz
Old sources:	TrialEmulation archive

Linking:

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