methyl {MCPAN} | R Documentation |
NTP bioassay of methyleugenol: 200 male rats were randomly assigned to 4 treatment groups with balanced sample size 50.
Individuals in treatment group 0, 1, 2, and 3 received doses of 0, 37, 75, and 150 mg methyleugenol per kg body weight, respectively.
The response variable tumour
is the presence of skin fibroma at time of death.
The variable death
gives individual time of death, with a final sacrifice of surviving animals at 730 days after begin of the assay.
data(methyl)
A data frame with 200 observations on the following 3 variables.
group
0
1
2
3
, specifying dose groups 0, 37, 75, and 150 mg/kg, respectivelytumour
death
National toxicology program (2000).
SD Peddada, GE Dinse, JK Haseman (2005): A survival-adjusted quantal response test for comparing tumour incidence rates. Applied Statistics 54, 51-61.
data(methyl) # raw tumour proportions: table(methyl[c("group", "tumour")]) # time of death: boxplot(death~group, data=methyl, horizontal=TRUE)