Package: Macarron
Version: 1.13.2
Title: Prioritization of potentially bioactive metabolic features from
        epidemiological and environmental metabolomics datasets
Authors@R: c(
  person("Amrisha", "Bhosle", email = "amrishabhosle@gmail.com", role = "aut"), 
  person("Ludwig", "Geistlinger", email = "Ludwig_Geistlinger@hms.harvard.edu", role = "aut"),
  person("Sagun", "Maharjan", email = "sagunmaharjann@gmail.com", role = c("aut", "cre"))
  )
Depends: R (>= 4.2.0), SummarizedExperiment
Imports: BiocParallel, DelayedArray, WGCNA, ff, data.table,
        dynamicTreeCut, Maaslin2, plyr, stats, psych, xml2, httr,
        RJSONIO, logging, methods, utils
Suggests: knitr, BiocStyle, optparse, testthat (>= 2.1.0), rmarkdown,
        markdown
Description: Macarron is a workflow for the prioritization of potentially bioactive
    metabolites from metabolomics experiments. Prioritization integrates strengths of 
    evidences of bioactivity such as covariation with a known metabolite, abundance
    relative to a known metabolite and association with an environmental or phenotypic
    indicator of bioactivity. Broadly, the workflow consists of stratified clustering
    of metabolic spectral features which co-vary in abundance in a condition, transfer
    of functional annotations, estimation of relative abundance and differential abundance
    analysis to identify associations between features and phenotype/condition.
VignetteBuilder: knitr
License: MIT + file LICENSE
URL: http://huttenhower.sph.harvard.edu/macarron
Encoding: UTF-8
biocViews: Sequencing, Metabolomics, Coverage, FunctionalPrediction,
        Clustering
BugReports: https://forum.biobakery.org/c/microbial-community-profiling/macarron
RoxygenNote: 7.3.2
git_url: https://git.bioconductor.org/packages/Macarron
git_branch: devel
git_last_commit: 143bd9d
git_last_commit_date: 2025-06-20
Repository: Bioconductor 3.22
Date/Publication: 2025-06-22
NeedsCompilation: no
Packaged: 2025-06-22 23:59:55 UTC; biocbuild
Author: Amrisha Bhosle [aut],
  Ludwig Geistlinger [aut],
  Sagun Maharjan [aut, cre]
Maintainer: Sagun Maharjan <sagunmaharjann@gmail.com>
Built: R 4.5.1; ; 2025-06-23 12:30:56 UTC; windows
