Second
            clustering analysis is based on the package ORIClust and its
            function ORICC1 and ORICC2 for one-stage or
            two-stage algorithm. Methodology is based within information
            criterion, clustering genes based on their profiles, while taking
            into account ordering of doses and monotonicity of dose-response
            relationship.    
          
        
          
        Analysis > ORIClust
        
          
        
          
        Screenshot
              of the main dialog box of ORIClust analysis
       
     
    
      
        Plot
              of the ORIClust results