rcellminer

This package is for version 3.10 of Bioconductor; for the stable, up-to-date release version, see rcellminer.

rcellminer: Molecular Profiles and Drug Response for the NCI-60 Cell Lines


Bioconductor version: 3.10

The NCI-60 cancer cell line panel has been used over the course of several decades as an anti-cancer drug screen. This panel was developed as part of the Developmental Therapeutics Program (DTP, http://dtp.nci.nih.gov/) of the U.S. National Cancer Institute (NCI). Thousands of compounds have been tested on the NCI-60, which have been extensively characterized by many platforms for gene and protein expression, copy number, mutation, and others (Reinhold, et al., 2012). The purpose of the CellMiner project (http://discover.nci.nih.gov/ cellminer) has been to integrate data from multiple platforms used to analyze the NCI-60 and to provide a powerful suite of tools for exploration of NCI-60 data.

Author: Augustin Luna, Vinodh Rajapakse, Fabricio Sousa

Maintainer: Augustin Luna <lunaa at cbio.mskcc.org>, Vinodh Rajapakse <vinodh.rajapakse at nih.gov>, Fathi Elloumi <fathi.elloumi at nih.gov>

Citation (from within R, enter citation("rcellminer")):

Installation

To install this package, start R (version "3.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("rcellminer")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("rcellminer")
Using rcellminer HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews CellBasedAssays, Cheminformatics, CopyNumberVariation, GeneExpression, Pharmacogenetics, Pharmacogenomics, Software, SystemsBiology, Visualization, aCGH, miRNA
Version 2.8.0
In Bioconductor since BioC 3.1 (R-3.2) (9 years)
License LGPL-3 + file LICENSE
Depends R (>= 3.2), Biobase, rcdk, fingerprint, rcellminerData
Imports stringr, gplots, ggplot2, methods, stats, utils, shiny
System Requirements
URL http://discover.nci.nih.gov/cellminer/
See More
Suggests knitr, RColorBrewer, sqldf, BiocGenerics, testthat, BiocStyle, jsonlite, d3heatmap, glmnet, foreach, doSNOW, parallel
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me rcellminerData
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package rcellminer_2.8.0.tar.gz
Windows Binary rcellminer_2.8.0.zip
Mac OS X 10.11 (El Capitan) rcellminer_2.8.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/rcellminer
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/rcellminer
Bioc Package Browser https://code.bioconductor.org/browse/rcellminer/
Package Short Url https://bioconductor.org/packages/rcellminer/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.10 Source Archive